Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC7971532 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Li Shizhe S van der Veen Jan Willem JW An Li L Stolinski JoEllyn J Johnson Christopher C Ferraris-Araneta Maria M Victorino Milalynn M Tomar Jyoti Singh JS Shen Jun J
PloS one 20210318 3
Abnormal cell membrane metabolism is associated with many neuropsychiatric disorders. Free phosphomonoesters and phosphodiesters, which can be detected by in vivo 31P magnetic resonance spectroscopy (MRS), are important cell membrane building blocks. However, the quantification of phosphoesters has been highly controversial even in healthy individuals due to overlapping signals from macromolecule membrane phospholipids (MP). In this study, high signal-to-noise ratio (SNR) cerebral 31P MRS spectr ...[more]