Local audit of empiric antibiotic therapy in bacteremia: A retrospective cohort study.

ABSTRACT:

Background

It is unclear if a local audit would be useful in providing guidance on how to improve local practice of empiric antibiotic therapy. We performed an audit of antibiotic therapy in bacteremia to evaluate the proportion and risk factors for inadequate empiric antibiotic coverage.

Methods

This retrospective cohort study included patients with positive blood cultures across 3 hospitals in Hamilton, Ontario, Canada during October of 2019. Antibiotic therapy was considered empiric if it was administered within 24 hours after blood culture collection. Adequate coverage was defined as when the isolate from blood culture was tested to be susceptible to the empiric antibiotic. A multivariable logistic regression model was used to predict inadequate empiric coverage. Diagnos

SUBMITTER: Bai AD 

PROVIDER: S-EPMC7971877 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature