Differential Impact of Education on Gray Matter Volume According to Sex in Cognitively Normal Older Adults: Whole Brain Surface-Based Morphometry.

ABSTRACT: Background: The effect of educational status on brain structural measurements depends on demographic and clinical factors in cognitively healthy older adults. Objectives: The current study aimed to evaluate the impact of interaction between years of education and sex on gray matter volume and to investigate whether cortical volume has a differential impact on cognitive function according to sex. Methods: One hundred twenty-one subjects between 60 and 85 years old were included in this study. Gray matter volume was evaluated by whole brain surface-based morphometry. Multiple regression analysis was used to analyze the effects of sex-cortical volume interactions on cognitive functions. Results: There was a significant interaction between years of education and sex

SUBMITTER: Kang DW 

PROVIDER: S-EPMC7973038 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature