WASP: a versatile, web-accessible single cell RNA-Seq processing platform.

ABSTRACT:

Background

The technology of single cell RNA sequencing (scRNA-seq) has gained massively in popularity as it allows unprecedented insights into cellular heterogeneity as well as identification and characterization of (sub-)cellular populations. Furthermore, scRNA-seq is almost ubiquitously applicable in medical and biological research. However, these new opportunities are accompanied by additional challenges for researchers regarding data analysis, as advanced technical expertise is required in using bioinformatic software.

Results

Here we present WASP, a software for the processing of Drop-Seq-based scRNA-Seq data. Our software facilitates the initial processing of raw reads generated with the ddSEQ or 10x protocol and generates demultiplexed gene expression matrices includ

SUBMITTER: Hoek A 

PROVIDER: S-EPMC7977290 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature