Molecular characterization of high-risk human papillomavirus (HR-HPV) in women in Lome, Togo.

ABSTRACT:

Background

The causative agent of cervical cancer referred to as Human papillomavirus (HPV) remains a real public health problem. Many countries in West Africa, such as Togo have no data on the high-risk HPV (HR-HPV) infection and genotypes distribution. In order to fill the knowledge gap in the field in Togo, the main objective of this study was to determine the prevalence of pre-cancerous lesions of the cervix and HR-HPV genotypes among Togolese women.

Methods

Samples were collected from 240 women by introducing a swab in the cervix. Then, the screening of precancerous cervical lesions using the visual inspection with acetic acid and lugol (VIA / VIL) was conducted. The HR-HPV genotypes were characterised by real-time multiplex PCR.

Results

Out of 240 women recruite

SUBMITTER: Kuassi-Kpede AP 

PROVIDER: S-EPMC7977574 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature