Comparison of Original and 2018 Lake Louise Criteria for Diagnosis of Acute Myocarditis: Results of a Validation Cohort.

ABSTRACT:

Purpose

To compare the diagnostic performance of the original Lake Louise criteria (LLC) and the 2018 LLC for the diagnosis of acute myocarditis and simultaneously validate previously reported cutoff values for parametric mapping techniques.

Materials and methods

A total of 40 patients with acute myocarditis and 26 control participants underwent cardiac MRI. Cardiac MRI protocol allowed for assessment of T2 signal intensity ratio, early gadolinium enhancement ratio, late gadolinium enhancement, T1 relaxation times, extracellular volume fraction, and T2 relaxation times. The original and the 2018 LLC were assessed, and differences between sensitivities and specificities were calculated with the McNemar test.

Results

The 2018 LLC yielded a sensitivity of 87.5% (95% conf

SUBMITTER: Luetkens JA 

PROVIDER: S-EPMC7978026 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature