Oscillatory and structural signatures of language plasticity in brain tumor patients: A longitudinal study.

ABSTRACT: Recent evidence suggests that damage to the language network triggers its functional reorganization. Yet, the spectro-temporal fingerprints of this plastic rearrangement and its relation to anatomical changes is less well understood. Here, we combined magnetoencephalographic recordings with a proxy measure of white matter to investigate oscillatory activity supporting language plasticity and its relation to structural reshaping. First, cortical dynamics were acquired in a group of healthy controls during object and action naming. Results showed segregated beta (13-28 Hz) power decreases in left ventral and dorsal pathways, in a time-window associated to lexico-semantic processing (~250-500 ms). Six patients with left tumors invading either ventral or dorsal regions performed the same namin

SUBMITTER: Amoruso L 

PROVIDER: S-EPMC7978121 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature