Age differences in functional network reconfiguration with working memory training.

ABSTRACT: Demanding cognitive functions like working memory (WM) depend on functional brain networks being able to communicate efficiently while also maintaining some degree of modularity. Evidence suggests that aging can disrupt this balance between integration and modularity. In this study, we examined how cognitive training affects the integration and modularity of functional networks in older and younger adults. Twenty three younger and 23 older adults participated in 10 days of verbal WM training, leading to performance gains in both age groups. Older adults exhibited lower modularity overall and a greater decrement when switching from rest to task, compared to younger adults. Interestingly, younger but not older adults showed increased task-related modularity with training. Furthermore, wherea

SUBMITTER: Iordan AD 

PROVIDER: S-EPMC7978135 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature