Polyploidy-associated paramutation in Arabidopsis is determined by small RNAs, temperature, and allele structure.

ABSTRACT: Paramutation is a form of non-Mendelian inheritance in which the expression of a paramutable allele changes when it encounters a paramutagenic allele. This change in expression of the paramutable alleles is stably inherited even after segregation of both alleles. While the discovery of paramutation and studies of its underlying mechanism were made with alleles that change plant pigmentation, paramutation-like phenomena are known to modulate the expression of other traits and in other eukaryotes, and many cases have probably gone undetected. It is likely that epigenetic mechanisms are responsible for the phenomenon, as paramutation forms epialleles, genes with identical sequences but different expression states. This could account for the intergenerational inheritance of the paramutated all

SUBMITTER: Bente H 

PROVIDER: S-EPMC7978347 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature