Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study.

ABSTRACT:

Objective

To compare risk factors, clinical presentation, and outcomes after posterior circulation arterial ischemic stroke (PCAIS) and anterior circulation arterial ischemic stroke (ACAIS) in neonates and children.

Methods

In this international multicenter observational study including neonates and children up to 18 years of age with arterial ischemic stroke (AIS), we compared clinical and radiologic features according to stroke location.

Results

Of 2,768 AIS cases, 507 (18%) were located in the posterior circulation, 1,931 (70%) in the anterior circulation, and 330 (12%) involved both. PCAIS was less frequent in neonates compared to children (8.8% vs 22%, p < 0.001). Children with PCAIS were older than children with ACAIS (median age 7.8 [interquartile range

SUBMITTER: Goeggel Simonetti B 

PROVIDER: S-EPMC7978473 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature