Validation of an admission coagulation panel for risk stratification of COVID-19 patients.

ABSTRACT:

Background

There is limited data on the markers of coagulation and hemostatic activation (MOCHA) profile in Coronavirus disease 2019 (COVID-19) and its ability to identify COVID-19 patients at risk for thrombotic events and other complications.

Methods

Hospitalized patients with confirmed SARS-COV-2 from four Atlanta hospitals were included in this observational cohort study and underwent admission testing of MOCHA parameters (plasma d-dimer, prothrombin fragment 1.2, thrombin-antithrombin complex, fibrin monomer). Clinical outcomes included deep vein thrombosis, pulmonary embolism, myocardial infarction, ischemic stroke, access line thrombosis, ICU admission, intubation and mortality.

Main results

Of 276 patients (mean age 59 ± 6.4 years, 47% female, 62% African Amer

SUBMITTER: Alabyad D 

PROVIDER: S-EPMC7979266 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature