Establishment of reference intervals of clinical chemistry analytes for the adult population in Egypt.

ABSTRACT:

Background

This is the first Egyptian nationwide study for derivation of reference intervals (RIs) for 34 major chemistry analytes. It was conducted as a part of the global initiative by the IFCC Committee on Reference Intervals and Decision Limits (C-RIDL) for establishing country-specific RIs based on a harmonized protocol.

Methods

691 apparently healthy volunteers aged ≥18 years were recruited from multiple regions in Egypt. Serum specimens were analyzed in two centers. The harmonization and standardization of test results were achieved by measuring value-assigned serum panel provided by C-RIDL. The RIs were calculated by parametric method. Sources of variation of reference values (RVs) were evaluated by multiple regression analysis. The need for partitioning by sex, age,

SUBMITTER: Baz H 

PROVIDER: S-EPMC7979267 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature