Peripheral immune profile of children with Talaromyces marneffei infections: a retrospective analysis of 21 cases.

ABSTRACT:

Background

Talaromyces marneffei (T. marneffei) is an opportunistic pathogen that infects immunodeficient children. The aim of the study is to determine the clinical features and peripheral immune state of Talaromyces marneffei (T. marneffei) infections in children for early detection and diagnosis.

Methods

We retrospectively reviewed 21 pediatric patients who were diagnosed with T. marneffei infections and were followed up in the Guangzhou Women and Children's Medical Center from January 2010 to January 2020. For each patient, we collected and analyzed clinical characteristics, peripheral immunological results, genetic tests, complications and prognosis.

Results

Common clinical features of the patients included fever (20/21, 95.24%), cough (17/21, 80.95%) and hepatom

SUBMITTER: Zeng Q 

PROVIDER: S-EPMC7980795 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature