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Furan Derivatives and Polyketides from the Fungus Irpex lacteus.


ABSTRACT: Eight new furan derivatives, irpexins A‒H (1‒8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic methods and Mosher ester reaction. All compounds shows no cytotoxicity to human MCF-7 and Hela cancer cell lines at the concentration of 10 μM.

SUBMITTER: Wang M 

PROVIDER: S-EPMC7981371 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature

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Furan Derivatives and Polyketides from the Fungus Irpex lacteus.

Wang Meng M   Li Zheng-Hui ZH   Isaka Masahiko M   Liu Ji-Kai JK   Feng Tao T  

Natural products and bioprospecting 20201112 2


Eight new furan derivatives, irpexins A‒H (1‒8), two new polyketides, irpexins I and J (9 and 10), together with nine known compounds were isolated from the fermentation of Irpex lacteus. The structures and absolute configurations were elucidated on the basis of extensive spectroscopic methods and Mosher ester reaction. All compounds shows no cytotoxicity to human MCF-7 and Hela cancer cell lines at the concentration of 10 μM. ...[more]

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