Early renal function trajectories, cytomegalovirus serostatus and long-term graft outcomes in kidney transplant recipients.

ABSTRACT:

Background

Improved recognition of factors influencing graft survival has led to better short-term kidney transplant outcomes. However, efforts to prevent long-term graft decline and improve graft survival have seen more modest improvements. The adoption of electronic health records has enabled better recording and identification of donor-recipient factors through the use of modern statistical techniques. We have previously shown in a prevalent renal transplant population that episodes of rapid deterioration are associated with graft loss.

Methods

Estimated glomerular filtration rates (eGFR) between 3 and 27 months after transplantation were collected from 310 kidney transplant recipients. We utilised a Bayesian approach to estimate the most likely eGFR trajectory as a smoot

SUBMITTER: Law JP 

PROVIDER: S-EPMC7981965 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature