Contingent negative variation: a biomarker of abnormal attention in functional movement disorders.

ABSTRACT:

Background and purpose

Contingent negative variation (CNV) is a negative cortical wave that precedes a pre-cued imperative stimulus requiring a quick motor response. It has been related to motor preparation and anticipatory attention. The aim was to ascertain whether the clinical improvement of functional movement disorders after physiotherapy would be associated with faster reaction times and modulation of CNV.

Methods

Motor performance and CNV were analysed during a pre-cued choice reaction time task with varying cue validity. Twenty-one patients with functional movement disorders and 13 healthy controls at baseline were compared. Patients then underwent physiotherapy. At follow-up after physiotherapy, patients were categorized as clinically improved (responders) or not im

SUBMITTER: Teodoro T 

PROVIDER: S-EPMC7982797 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature