Left atrial 4D flow cardiovascular magnetic resonance: a reproducibility study in sinus rhythm and atrial fibrillation.

ABSTRACT:

Background

Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) allows sophisticated quantification of left atrial (LA) blood flow, and could yield novel biomarkers of propensity for intra-cardiac thrombus formation and embolic stroke. As reproducibility is critically important to diagnostic performance, we systematically investigated technical and temporal variation of LA 4D flow in atrial fibrillation (AF) and sinus rhythm (SR).

Methods

Eighty-six subjects (SR, n = 64; AF, n = 22) with wide-ranging stroke risk (CHA₂DS₂VASc 0-6) underwent LA 4D flow assessment of peak and mean velocity, vorticity, vortex volume, and stasis. Eighty-five (99%) underwent a second acquisition within the same session, and 74 (86%) also returned at 30 (27-35) d

SUBMITTER: Spartera M 

PROVIDER: S-EPMC7983287 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature