Supplementation of green coffee bean extract in healthy overweight subjects increases lean mass/fat mass ratio: A randomized, double-blind clinical study.

ABSTRACT:

Objective

In this study, we have demonstrated that supplementation of a complex of chlorogenic acid isomers (CGA-7^TM) could significantly mitigate the risk of obesity in healthy overweight subjects.

Method

In a double-blind, placebo-controlled clinical study, healthy overweight (body mass index ⩾ 25 to <30 kg/m²) male and female subjects (N = 71) were randomly allocated to receive 500 mg CGA-7 or placebo daily for 12 weeks. Changes in body weight and body mass index were recorded alongside vital signs and anthropometric measurements at week 4, 8 and 12. Body composition was assessed at baseline and the end of treatment using dual-energy X-ray absorptiometry. Safety analysis included serum biochemical and haematological assessments and measurement

SUBMITTER: Sudeep HV 

PROVIDER: S-EPMC7983441 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature