Hepcidin response to interval running exercise is not affected by oral contraceptive phase in endurance-trained women.

ABSTRACT: The use of oral contraceptives (OCs) by female athletes may lead to improved iron status, possibly through the regulation of hepcidin by sex hormones. The present work investigates the response of hepcidin and interleukin-6 (IL-6) to an interval exercise in both phases of the OC cycle. Sixteen endurance-trained OC users (age 25.3 ± 4.7 years; height 162.4 ± 5.7 cm; body mass 56.0 ± 5.7 kg; body fat percentage 24.8 ± 6.0%; peak oxygen consumption [VO_2peak ]: 47.4 ± 5.5 mL min^-1 kg^-1 ) followed an identical interval running protocol during the withdrawal and active pill phases of the OC cycle. This protocol consisted of 8 × 3 minutes bouts at 85% VO_2peak speed with 90 seconds recovery intervals. Blood samples were collected pre-exercise, and at 0 h

SUBMITTER: Alfaro-Magallanes VM 

PROVIDER: S-EPMC7984293 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature