Manual Segmentation of MS Cortical Lesions Using MRI: A Comparison of 3 MRI Reading Protocols.

ABSTRACT:

Background and purpose

Double inversion recovery has been suggested as the MR imaging contrast of choice for segmenting cortical lesions in patients with multiple sclerosis. In this study, we sought to determine the utility of double inversion recovery for cortical lesion identification by comparing 3 MR imaging reading protocols that combine different MR imaging contrasts.

Materials and methods

Twenty-five patients with relapsing-remitting MS and 3 with secondary-progressive MS were imaged with 3T MR imaging by using double inversion recovery, dual fast spin-echo proton-density/T2-weighted, 3D FLAIR, and 3D T1-weighted imaging sequences. Lesions affecting the cortex were manually segmented by using the following 3 MR imaging reading protocols: Protocol 1 (P1) used all avail

SUBMITTER: Maranzano J 

PROVIDER: S-EPMC7984679 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature