Phylogenomic analysis of COVID-19 summer and winter outbreaks in Hong Kong: An observational study.

ABSTRACT:

Background

Viral genomic surveillance is vital for understanding the transmission of COVID-19. In Hong Kong, breakthrough outbreaks have occurred in July (third wave) and November (fourth wave) 2020. We used whole viral genome analysis to study the characteristics of these waves.

Methods

We analyzed 509 SARS-CoV-2 genomes collected from Hong Kong patients between 22nd January and 29th November, 2020. Phylogenetic and phylodynamic analyses were performed, and were interpreted with epidemiological information.

Findings

During the third and fourth waves, diverse SARS-CoV-2 genomes were identified among imported infections. Conversely, local infections were dominated by a single lineage during each wave, with 96.6% (259/268) in the third wave and 100% (73/73) in th

SUBMITTER: Chan WM 

PROVIDER: S-EPMC7985010 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature