Effects of acute heat stress on protein expression and histone modification in the adrenal gland of male layer-type country chickens.

ABSTRACT: The adrenal gland responds to heat stress by epinephrine and glucocorticoid release to alleviate the adverse effects. This study investigated the effect of acute heat stress on the protein profile and histone modification in the adrenal gland of layer-type country chickens. A total of 192 roosters were subject to acute heat stress and thereafter classified into a resistant or susceptible group according to body temperature change. The iTRAQ analysis identified 80 differentially expressed proteins, in which the resistant group had a higher level of somatostatin and hydroxy-δ-5-steroid dehydrogenase but a lower parathymosin expression in accordance with the change of serum glucocorticoid levels. Histone modification analysis identified 115 histone markers. The susceptible group had a higher

SUBMITTER: Zheng HT 

PROVIDER: S-EPMC7985386 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature