Association of Age With SARS-CoV-2 Antibody Response.

ABSTRACT:

Importance

Accumulating evidence suggests that children infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are more likely to manifest mild symptoms and are at a lower risk of developing severe respiratory disease compared with adults. It remains unknown how the immune response in children differs from that of adolescents and adults.

Objective

To investigate the association of age with the quantity and quality of SARS-CoV-2 antibody responses.

Design, setting, and participants

This cross-sectional study used 31 426 SARS-CoV-2 antibody test results from pediatric and adult patients. Data were collected from a New York City hospital from April 9 to August 31, 2020. The semiquantitative immunoglobin (Ig) G levels were compared between 85 pediatric

SUBMITTER: Yang HS 

PROVIDER: S-EPMC7985726 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature