Post-exercise intramuscular O₂ supply is tightly coupled with a higher proximal-to-distal ATP synthesis rate in human tibialis anterior.

ABSTRACT:

Key points

The post-exercise recovery of phosphocreatine, a measure of the oxidative capacity of muscles, as assessed by ³¹ P MR spectroscopy, shows a striking increase from distal to proximal along the human tibialis anterior muscle. To investigate why this muscle exhibits a greater oxidative capacity proximally, we tested whether the spatial variation in phosphocreatine recovery rate is related to oxygen supply, muscle fibre type or type of exercise. We revealed that oxygen supply also increases from distal to proximal along the tibialis anterior, and that it strongly correlated with phosphocreatine recovery. Carnosine level, a surrogate measure for muscle fibre type was not different between proximal and distal, and type of exercise did not affect the gradient in phos

SUBMITTER: Heskamp L 

PROVIDER: S-EPMC7986184 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature