Direct impact of commonly used dietary emulsifiers on human gut microbiota.

ABSTRACT:

Background

Epidemiologic evidence and animal studies implicate dietary emulsifiers in contributing to the increased prevalence of diseases associated with intestinal inflammation, including inflammatory bowel diseases and metabolic syndrome. Two synthetic emulsifiers in particular, carboxymethylcellulose and polysorbate 80, profoundly impact intestinal microbiota in a manner that promotes gut inflammation and associated disease states. In contrast, the extent to which other food additives with emulsifying properties might impact intestinal microbiota composition and function is not yet known.

Methods

To help fill this knowledge gap, we examined here the extent to which a human microbiota, maintained ex vivo in the MiniBioReactor Array model, was impacted by 20 different comm

SUBMITTER: Naimi S 

PROVIDER: S-EPMC7986288 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature