Network analyses in microbiome based on high-throughput multi-omics data.

ABSTRACT: Together with various hosts and environments, ubiquitous microbes interact closely with each other forming an intertwined system or community. Of interest, shifts of the relationships between microbes and their hosts or environments are associated with critical diseases and ecological changes. While advances in high-throughput Omics technologies offer a great opportunity for understanding the structures and functions of microbiome, it is still challenging to analyse and interpret the omics data. Specifically, the heterogeneity and diversity of microbial communities, compounded with the large size of the datasets, impose a tremendous challenge to mechanistically elucidate the complex communities. Fortunately, network analyses provide an efficient way to tackle this problem, and several netw

SUBMITTER: Liu Z 

PROVIDER: S-EPMC7986608 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature