Effect of acute alcohol intoxication on mortality, coagulation, and fibrinolysis in trauma patients.

ABSTRACT:

Background

The effect of alcohol on the outcome and fibrinolysis phenotype in trauma patients remains unclear. Hence, we performed this study to determine whether alcohol is a risk factor for mortality and fibrinolysis shutdown in trauma patients.

Materials and methods

A total of 686 patients who presented to our trauma center and underwent rotational thromboelastometry were included in the study. The primary outcome was in-hospital mortality. Logistic regression analysis was performed to determine whether alcohol was an independent risk factor for in-hospital mortality and fibrinolysis shutdown.

Results

The rate of in-hospital mortality was 13.8% and blood alcohol was detected in 27.7% of the patients among our study population. The patients in the alcohol-positive g

SUBMITTER: Wang IJ 

PROVIDER: S-EPMC7987171 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature