A Prospective Evaluation of Swallowing and Speech in Patients with Neurofibromatosis Type 2.

ABSTRACT: Objective  Neurofibromatosis type 2 (NF2) patients report that swallowing and speech problems significantly affect their quality of life, but the etiology of these phenomena is poorly understood. Swallowing and speech deficits may arise due to the neuropathy of involved nerves, due to posterior fossa tumor growth, or as iatrogenic effects from neurosurgical procedures to remove these tumors. This study aims to identify the natural history of swallowing and speech deficits in an NF2 cohort and to characterize the factors that may lead to those deficits. Methods  Subjects ( n  = 168) were enrolled in a prospective, longitudinal study of NF2 with yearly imaging and clinical exams. The patients completed a self-reported questionnaire that included responses regarding subje

SUBMITTER: Rajendran S 

PROVIDER: S-EPMC7987378 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature