Dietary macronutrients do not differently affect postprandial vascular endothelial function in apparently healthy overweight and slightly obese men.

ABSTRACT:

Purpose

Well-designed trials comparing side-by-side effects of macronutrients on postprandial endothelial function are missing. Therefore, we investigated under well-controlled and isocaloric condition effects of fat, carbohydrates, and protein on postprandial endothelial function as assessed by brachial artery flow-mediated vasodilation (FMD), an important non-invasive technique to assess endothelial function.

Methods

Eighteen apparently healthy overweight and slightly obese men (BMI 26.0-35.0 kg/m²) completed this randomized, double-blinded, cross-over trial. The study consisted of three test days each separated by a wash-out period of at least 1 week. After an overnight fast, men received an isocaloric meal providing 3987 kJ (953 kcal) that was either high in d

SUBMITTER: Smeets ETHC 

PROVIDER: S-EPMC7987601 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature