Binocular integration of retinal motion information underlies optic flow processing by the cortex.

ABSTRACT: Locomotion creates various patterns of optic flow on the retina, which provide the observer with information about their movement relative to the environment. However, it is unclear how these optic flow patterns are encoded by the cortex. Here, we use two-photon calcium imaging in awake mice to systematically map monocular and binocular responses to horizontal motion in four areas of the visual cortex. We find that neurons selective to translational or rotational optic flow are abundant in higher visual areas, whereas neurons suppressed by binocular motion are more common in the primary visual cortex. Disruption of retinal direction selectivity in Frmd7 mutant mice reduces the number of translation-selective neurons in the primary visual cortex and translation- and rotation-selective neuro

SUBMITTER: Rasmussen RN 

PROVIDER: S-EPMC7987724 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature