In Vivo Image-Based 4D Modeling of Competent and Regurgitant Mitral Valve Dynamics.

ABSTRACT:

Background

In vivo characterization of mitral valve dynamics relies on image analysis algorithms that accurately reconstruct valve morphology and motion from clinical images. The goal of such algorithms is to provide patient-specific descriptions of both competent and regurgitant mitral valves, which can be used as input to biomechanical analyses and provide insights into the pathophysiology of diseases like ischemic mitral regurgitation (IMR).

Objective

The goal is to generate accurate image-based representations of valve dynamics that visually and quantitatively capture normal and pathological valve function.

Methods

We present a novel framework for 4D segmentation and geometric modeling of the mitral valve in real-time 3D echocardiography (rt-3DE), an imaging modal

SUBMITTER: Aly AH 

PROVIDER: S-EPMC7988343 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature