Association of spontaneous abortion with all cause and cause specific premature mortality: prospective cohort study.

ABSTRACT:

Objective

To investigate the association of spontaneous abortion with the risk of all cause and cause specific premature mortality (death before the age of 70).

Design

Prospective cohort study.

Setting

The Nurses' Health Study II (1993-2017), United States.

Participants

101 681 ever gravid female nurses participating in the Nurses' Health Study II.

Main outcomes measures

Lifetime occurrence of spontaneous abortion in pregnancies lasting less than 6 months, determined by biennial questionnaires. Hazard ratios and 95% confidence intervals for all cause and cause specific premature death according to the occurrence of spontaneous abortion, estimated with time dependent Cox proportional hazards models.

Results

During 24 years of follow-up, 2936 premat

SUBMITTER: Wang YX 

PROVIDER: S-EPMC7988453 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature