Physical activity may not be associated with long-term risk of dementia and Alzheimer's disease.

ABSTRACT:

Background

While it is well established that physical activity is associated with reduced risk of vascular and nonvascular outcomes as well as mortality, evidence on the association between physical activity and dementia is inconsistent. We aimed to assess the associations of physical activity with the risk of dementia and Alzheimer's disease (AD).

Material and methods

We analysed data on 2394 apparently healthy men with good baseline cognitive function from the prospective population-based Kuopio Ischaemic Heart Disease study. We assessed habits of physical activity at baseline using a 12-month leisure time physical activity (LTPA) questionnaire. Using Cox regression, we calculated hazard ratios adjusted for body mass index, systolic blood pressure, smoking status, history

SUBMITTER: Kunutsor SK 

PROVIDER: S-EPMC7988584 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature