Following up of Surgical Treated Human Liver Cystic Echinococcosis: A Proteomics Approach.

ABSTRACT:

Background

Cystic echinococcosis (CE) is one of the most important parasitic zoonosis in the world. Post-surgery follow up in CE patients is an important non-solved problem up to now. Therefore, the investigations on this problematic issue would be very applicable in the view of CE clinical treatment.

Methods

A total of 24 confirmed liver CE patients sera including eight sera before surgery (BS), eight sera three months post-surgery (3MPS), and eight sera six months post-surgery (6MPS) were used in the present study. Proteomics methods including 2DE and LC-MS/MS were performed on the specimens followed by bioinformatics analysis such as Gene Ontology (GO) and Protein-Protein Interaction (PPI) network analysis.

Results

A total of 235 proteins were detected of which 12

SUBMITTER: Sadjjadi FS 

PROVIDER: S-EPMC7988678 | biostudies-literature | 2021 Jan-Mar

REPOSITORIES: biostudies-literature