The link between COVID-19 and VItamin D (VIVID): A systematic review and meta-analysis.

ABSTRACT:

Background

Disease severity and mortality rates due to COVID-19 infection are greater in the elderly and chronically ill patients, populations at high risk for vitamin D deficiency. Vitamin D plays an important role in immune function and inflammation. This systematic review and meta-analysis assesses the impact of vitamin D status and supplementation on COVID-19 related mortality and health outcomes.

Methods

We searched four databases until December 18th 2020, and trial registries until January 20th 2021. Two reviewers screened the studies, collected data, assessed the risk of bias, and graded the evidence for each outcome across studies, independently and in duplicate. Pre-specified outcomes of interest were mortality, ICU admission, invasive and non-invasive ventilation,

SUBMITTER: Bassatne A 

PROVIDER: S-EPMC7989070 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature