Reported maternal childhood maltreatment experiences, amygdala activation and functional connectivity to infant cry.

ABSTRACT: Maternal childhood maltreatment experiences (CMEs) may influence responses to infants and affect child outcomes. We examined associations between CME and mothers' neural responses and functional connectivity to infant distress. We hypothesized that mothers with greater CME would exhibit higher amygdala reactivity and amygdala-supplementary motor area (SMA) functional connectivity to own infant's cries. Postpartum mothers (N = 57) assessed for CME completed an functional magnetic resonance imaging task with cry and white-noise stimuli. Amygdala region-of-interest and psychophysiological interaction analyses were performed. Our models tested associations of CME with activation and connectivity during task conditions (own/other and cry/noise). Exploratory analyses with parenting behaviors wer

SUBMITTER: Olsavsky AK 

PROVIDER: S-EPMC7990072 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature