Dynamic PET/CT Imaging of ⁶⁸Ga-FAPI-04 in Chinese Subjects.

ABSTRACT: This study aims to further explore dynamic ⁶⁸Ga-FAPI-04 PET/CT imaging of healthy Chinese subjects and lung cancer patients. Moreover, the variability of ⁶⁸Ga-FAPI-04 uptake in normal organs was measured to provide a basis for analyzing its biological distribution, interpreting auxiliary images, determining the reliability of image quantification, and monitoring treatment. Six patients (3 subjects without tumors and 3 lung cancer patients) separately underwent ⁶⁸Ga-FAPI-04 and 2-[¹⁸F]FDG PET/CT imaging within 1 week. The biodistribution and internal radiation dosimetry were reported and compared with data previously obtained from Caucasian patients. Moreover, the mean SUV (standardized uptake value) was normalized to body mass or to lean body mas

SUBMITTER: Wang S 

PROVIDER: S-EPMC7991833 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature