Reduced Albumin Concentration Predicts Weight Gain and Higher <i>Ad Libitum</i> Energy Intake in Humans.

ABSTRACT:

Objective

Circulating albumin is negatively associated with adiposity but whether it is associated with increased energy intake, lower energy expenditure or weight gain has not been examined.

Methods

In study 1 (n=238; 146 men), we evaluated whether fasting albumin concentration was associated with 24-h energy expenditure and ad libitum energy intake. In study 2 (n=325;167 men), we evaluated the association between plasma albumin and change in weight and body composition.

Results

After adjustment for known determinants of energy intake lower plasma albumin concentration was associated with greater total daily energy intake (β= 89.8 kcal/day per 0.1 g/dl difference in plasma albumin, p=0.0047). No associations were observed between plasma albumin c

SUBMITTER: Basolo A 

PROVIDER: S-EPMC7991842 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature