Ten-Year Follow-up of Persons With Sun-Damaged Skin Associated With Subsequent Development of Cutaneous Squamous Cell Carcinoma.

ABSTRACT:

Importance

Risk of cutaneous squamous cell carcinoma (cSCC) after the diagnosis of actinic keratosis (AK) has not been studied during long follow-up periods.

Objective

To estimate the risk up to 10 years and identify risk factors for cSCC development.

Design, setting, and participants

This longitudinal cohort study, performed from January 1, 2009, to February 29, 2020, examined Kaiser Permanente Northern California patients with AK and control patients matched 1:1 on age, sex, race/ethnicity, medical center, and date of the initial diagnosis plus 30 days in the patients with AK.

Exposures

Patients with AK and control participants were followed up for up to 10 years for incidence of cSCC.

Main outcomes and measures

Incident cSCC was obtained from patholog

SUBMITTER: Madani S 

PROVIDER: S-EPMC7992022 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature