Cross-kingdom inhibition of bacterial virulence and communication by probiotic yeast metabolites.

ABSTRACT:

Background

Probiotic milk-fermented microorganism mixtures (e.g., yogurt, kefir) are perceived as contributing to human health, and possibly capable of protecting against bacterial infections. Co-existence of probiotic microorganisms are likely maintained via complex biomolecular mechanisms, secreted metabolites mediating cell-cell communication, and other yet-unknown biochemical pathways. In particular, deciphering molecular mechanisms by which probiotic microorganisms inhibit proliferation of pathogenic bacteria would be highly important for understanding both the potential benefits of probiotic foods as well as maintenance of healthy gut microbiome.

Results

The microbiome of a unique milk-fermented microorganism mixture was determined, revealing a predominance of the fung

SUBMITTER: Malka O 

PROVIDER: S-EPMC7992341 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature