Long-term effect of aripiprazole lauroxil on health-related quality of life in patients with schizophrenia.

ABSTRACT:

Background

This post hoc analysis of clinical trial data evaluated long-term, self-reported mental and physical health-related quality of life (HRQoL) scores in schizophrenia patients receiving aripiprazole lauroxil (AL), an atypical long-acting injectable (LAI) antipsychotic approved for the treatment of schizophrenia in adults.

Methods

The study population included 291 stable schizophrenia outpatients enrolled in 2 consecutive long-term safety studies of AL given every 4 weeks for up to 124 weeks. HRQoL was measured using the SF-36v2® Health Survey (SF-36v2) over the course of the follow-up. The primary outcome was change in SF-36v2 mental component summary (MCS) and physical component summary (PCS) scores from baseline to 124 weeks. To contextualize these scores, descript

SUBMITTER: McEvoy JP 

PROVIDER: S-EPMC7992347 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature