Dynamic modeling and optimal control of cystic echinococcosis.

ABSTRACT:

Background

Cystic echinococcosis is one of the most severe helminth zoonosis with a drastic impact on human health and livestock industry. Investigating optimal control strategy and assessing the crucial factors are essential for developing countermeasures to mitigate this disease.

Methods

Two compartment models were formulated to study the dynamics of cystic echinococcosis transmission, to evaluate the effectiveness of various control measures, and to find the optimal control strategy. Sensitive analyses were conducted by obtaining PRCCs and contour plot was used to evaluate the effect of key parameters on the basic reproduction number. Based on forward-backward sweep method, numerical simulations were employed to investigate effects of key factors on the transmission of cy

SUBMITTER: Rong X 

PROVIDER: S-EPMC7992812 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature