The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men.

ABSTRACT:

Context

The hormone kisspeptin has crucial and well-characterized roles in reproduction. Emerging data from animal models also suggest that kisspeptin has important metabolic effects including modulation of food intake. However, to date there have been no studies exploring the effects of kisspeptin on brain responses to food stimuli in humans.

Objective

This work aims to investigate the effects of kisspeptin administration on brain responses to visual food stimuli and psychometric parameters of appetite, in healthy men.

Design

A double-blinded, randomized, placebo-controlled, crossover study was conducted.

Participants

Participants included 27 healthy, right-handed, eugonadal men (mean ± SEM: age 26.5 ± 1.1 years; body mass index 23.9 ± 0.4 kg/m2).

Intervent

SUBMITTER: Yang L 

PROVIDER: S-EPMC7993584 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature