The Renin-Angiotensin System, Hypertension, and SARS-CoV-2 Infection: a Review.

ABSTRACT:

Purpose of review

This review focuses on the associations between the renin-angiotensin system, hypertension, and severe acute respiratory syndrome (SARS-COV-2) infection. A brief prelude on the current state of affairs with COVID-19 is given. In addition to an overview of ACE2, Ang II, and Ang (1-7), this review presents a brief statement on hypertension, including the function of enzymes involved in the control of hypertension, cardiovascular disease, diabetes mellitus, and other malignancies.

Recent findings

There is currently no data in support of the concerns raised with the use of ACEIs/ARBs. Many researchers have voiced concerns that the use of ACEIs and ARBs may increase tissue ACE2 levels. These researchers therefore recommend that individuals on ACEIs/ARB's medicat

SUBMITTER: Gathiram P 

PROVIDER: S-EPMC7993901 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature