Vaginal bleeding and nausea in early pregnancy as predictors of clinical pregnancy loss.

ABSTRACT:

Background

Although nausea and vaginal bleeding are commonly experienced in early pregnancy, their prognostic value in predicting clinical pregnancy loss is not well understood.

Objective

This study aimed to understand whether timing of bleeding and nausea symptoms can be used to predict risk of pregnancy loss among women with ultrasound-confirmed pregnancies.

Study design

A cohort of 701 women with clinically confirmed pregnancies and 1 to 2 previous pregnancy losses were preconceptionally enrolled in the Effects of Aspirin in Gestation and Reproduction trial (2006-2012). Participants completed daily symptom diaries from 2 to 8 weeks' gestation and were prospectively monitored for detection of pregnancy loss. The risk of pregnancy loss was estimated for each observed

SUBMITTER: DeVilbiss EA 

PROVIDER: S-EPMC7994023 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature