Genetic variations in the Myostatin gene affecting growth traits in sheep.

ABSTRACT:

Background and aim

Sheep productivity in developing countries is crucial, as this animal is an essential source of meat and wool. Myostatin (MSTN) plays an important role in the regulation of muscle mass through the regulation of muscle growth, differentiation, and regeneration. The present study sought to investigate genetic variation in the first intron of the MSTN gene and the association of variants with growth traits in major sheep breeds in Egypt (Barki, Ossimi, and Rahmani) and Saudi Arabia (Najdi) using polymerase chain reaction (PCR) and sequencing.

Materials and methods

Blood samples were collected, and DNA was extracted from 75 animals. A 386 bp fragment in the first intron of the MSTN gene was amplified using PCR. Polymorphic sites wer

SUBMITTER: Osman NM 

PROVIDER: S-EPMC7994128 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature