Social isolation and risk of heart disease and stroke: analysis of two large UK prospective studies.

ABSTRACT:

Background

Social isolation has been associated with increased risk of coronary heart disease and stroke. However, it is unclear whether the associations differ between fatal and non-fatal events or by the type of isolation (living alone or having few social contacts). We aimed to examine these associations in two large UK prospective cohorts.

Methods

Million Women Study and UK Biobank participants without previous coronary heart disease or stroke who provided data in median year 2010 (IQR 2009-2011) on social contacts were included in this prospective analysis. Participants were followed up to median year 2017 (2017-2017) by electronic linkage to national hospital and death records. Risk ratios (RRs) were calculated using Cox regression for first coronary heart disease and

SUBMITTER: Smith RW 

PROVIDER: S-EPMC7994247 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature