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Association of Maternal Body Mass Index With Risk of Infant Mortality: A Dose-Response Meta-Analysis.


ABSTRACT: Objective: This study presumed that a high or low body mass index (BMI) might increase the risk of infant mortality. Therefore, a meta-analysis was performed to systematically assess the association between maternal BMI and the risk of infant mortality. Methods: The electronic databases, including Pubmed, Embase database, and Cochrane Library, were systemically searched by two investigators from inception to November 26th, 2020, with no language restriction. In parallel, a dose-response was assessed. Results: Finally, 22 cohort studies involving 13,532,293 participants were included into this paper, which showed that compared with normal BMI, maternal overweight significantly increased the risks of infant mortality [risk ratio (RR), 1.16; 95% confidence interval (CI),

SUBMITTER: Huo N 

PROVIDER: S-EPMC7994890 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature