Graphene Sheets with Defined Dual Functionalities for the Strong SARS-CoV-2 Interactions.

ABSTRACT: Search of new strategies for the inhibition of respiratory viruses is one of the urgent health challenges worldwide, as most of the current therapeutic agents and treatments are inefficient. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic and has taken lives of approximately two million people to date. Even though various vaccines are currently under development, virus, and especially its spike glycoprotein can mutate, which highlights a need for a broad-spectrum inhibitor. In this work, inhibition of SARS-CoV-2 by graphene platforms with precise dual sulfate/alkyl functionalities is investigated. A series of graphene derivatives with different lengths of aliphatic chains is synthesized and is investigated for their ability to inhibit SARS-CoV-2 and felin

SUBMITTER: Donskyi IS 

PROVIDER: S-EPMC7995151 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature