Efficacy of hypophysectomy for the treatment of hypersomatotropism-induced diabetes mellitus in 68 cats.

ABSTRACT:

Background

Hypersomatotropism (HST) is an increasingly recognized endocrinopathy in cats and is mostly described associated with diabetes mellitus (DM).

Objectives

To evaluate the efficacy and safety of transsphenoidal hypophysectomy in treating HST and DM in cats.

Animals

Sixty-eight client-owned cats with HST and DM treated by transsphenoidal hypophysectomy.

Methods

Retrospective cohort study. Medical records were reviewed for glycemic control and serum insulin-like growth factor-1 (IGF-1) concentrations. Postoperative complications, death within 4 weeks, and proportion achieving diabetic remission were recorded. Survival times and DM-free intervals were calculated.

Results

Fifty-eight cats (85.3%) were alive 4 weeks postoperatively with 10 (15%) posto

SUBMITTER: Fenn J 

PROVIDER: S-EPMC7995378 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature